ea0007oc25 | Endocrine tumours | BES2004
Emery M
, Merulli C
, Bonner S
, Nanzer A
, Musat M
, Galloway M
, Grossman A
, Korbonits M
It has been reported that both normal pituitary and pituitary tumours express PPAR gamma, a nuclear hormone receptor, the expression being much more abundant in pituitary tumours. It has also been suggested that PPAR gamma agonists, such as the thiazolidenediones, could be used as a therapeutic option for pituitary tumours. In order to investigate this further, 'Real time' PCR was used to assess PPAR gamma RNA expression, and Western blotting and immunohistochemistry was used ...